Which Drugs Can Cause Chloasma?
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Chloasma, also known as melasma, is a common skin condition that causes dark, discolored patches on the face. It is most often seen in women, especially those with darker skin tones. Chloasma can be caused by a variety of factors, including sun exposure, hormones, and certain medications.
Medications that can cause chloasma
A number of medications can cause chloasma, including:
Birth control pills
Hormone replacement therapy
Anticonvulsants
Antipsychotics
Photosensitizing drugs
Birth control pills
Birth control pills are one of the most common causes of chloasma. The hormones in birth control pills can stimulate the production of melanin, the pigment that gives skin its color. This can lead to the development of dark patches on the face.
Hormone replacement therapy
Hormone replacement therapy (HRT) is another common cause of chloasma. HRT is used to treat symptoms of menopause, such as hot flashes and night sweats. The hormones in HRT can also stimulate the production of melanin, leading to chloasma.
Anticonvulsants
Anticonvulsants are medications that are used to treat seizures. Some anticonvulsants, such as phenytoin and carbamazepine, can cause chloasma.
Antipsychotics
Antipsychotics are medications that are used to treat schizophrenia and other mental health conditions. Some antipsychotics, such as haloperidol and chlorpromazine, can cause chloasma.
Photosensitizing drugs
Photosensitizing drugs are medications that make the skin more sensitive to sunlight. This can lead to the development of chloasma, especially if the skin is exposed to sunlight for long periods of time. Some photosensitizing drugs include:
Tetracyclines
Sulfonamides
Quinolones
Thiazides
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Treatment for chloasma
The treatment for chloasma depends on the underlying cause. If the chloasma is caused by a medication, the doctor may recommend stopping the medication or switching to a different medication. If the chloasma is caused by sun exposure, the doctor may recommend using sunscreen and avoiding prolonged sun exposure.
There are also a number of topical treatments that can be used to lighten the dark patches of chloasma. These treatments include:
Hydroquinone
Kojic acid
Azelaic acid
Tretinoin
These treatments can be effective in lightening the dark patches of chloasma, but they may take several months to work. It is important to use these treatments as directed by the doctor and to avoid sun exposure while using them.
Prevention of chloasma
The best way to prevent chloasma is to avoid the factors that can cause it. These include:
Sun exposure
Hormonal changes
Medications
If you are at risk for developing chloasma, it is important to talk to your doctor about ways to prevent it.
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